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ISL1 Antibody / Islet 1

ISL1 is a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

P61371

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 156-185 from the human protein was used as the immunogen for this ISL1 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the ISL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This ISL1 antibody is available for research use only.

Storage Conditions

Aliquot the ISL1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the ISL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Chicken, Rat, Zebrafish

Image Legend

ISL1 antibody western blot analysis in MDA-MB231 lysate. Predicted molecular weight ~39 kDa.

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