SIRT3 Antibody
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q9NTG7
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 56-84 from the human protein was used as the immunogen for this SIRT3 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the SIRT3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SIRT3 antibody is available for research use only.
Storage Conditions
Aliquot the SIRT3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the SIRT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
SIRT3 antibody western blot analysis in MDA-MB453 lysate. Predicted molecular weight: 44/28 kDa (full/processed)
Documents
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