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Flt3-L Rabbit Polyclonal Antibody

Product Specifications

Background

Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910) -positive classical DCs and their CD103 (ITGAE; MIM 604682) -positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]) .[supplied by OMIM, Jan 2011], function:Stimulates the proliferation of early hematopoietic cells. Synergizes well with a number of other colony stimulating factors and interleukins., subunit:Homodimer (isoform 2) .

Product Name Alternative

FLT3LG; Fms-related tyrosine kinase 3 ligand; Flt3 ligand; Flt3L; SL cytokine

Gene Name

FLT3LG

Gene ID

2323

Swiss Prot

P49771

Host

Rabbit

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, ELISA

Field of Research

Cytokine-cytokine receptor interaction; Hematopoietic cell lineage; Pathways in cancer

Purification

Affinity purification

Dilution

WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Molecular Weight

26kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Frequently Asked Questions

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