RNF8 Antibody

The protein encoded by this gene contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

O76064

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 335-364 from the human protein was used as the immunogen for this RNF8 antibody.

Clonality

Polyclonal

Isotype

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the RNF8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This RNF8 antibody is available for research use only.

Storage Conditions

Aliquot the RNF8 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the RNF8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

RNF8 antibody western blot analysis in CEM lysate. Predicted molecular weight: 55/51 kDa (isoforms 1/3), but may be observed at larger sizes due to ubiquitination.