sPLA2-X Inhibitor 31
Product Specifications
UNSPSC Description
sPLA2-X Inhibitor 31 is a selective secreted phospholipase A2 type X (sPLA2-X) inhibitor with IC50s of 26 nM, 310 nM, and 2230 nM for sPLA2-X, sPLA2-IIa, and sPLA2-V, respectively[1].
Target Antigen
Phospholipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sPLA2-X_Inhibitor_31.html
Solubility
10 mM in DMSO
Smiles
FC(F)(F)OC1=CC=C(C=C(C(N)=O)N2C3=CC(CCC(O)=O)=CC=C3)C2=C1
Molecular Weight
392.33
References & Citations
[1]Knerr L, et al. Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A2 Type X(sPLA2-X) Inhibitors. ACS Med Chem Lett. 2018 Jun 23;9(7):594-599.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-112605/sPLA2-X-Inhibitor-31-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-112605/
Clinical Information
No Development Reported
CAS Number
2241025-50-1
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