IL1R2 Antibody
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I (IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P27930
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 273-300 from the human protein was used as the immunogen for this IL1R2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the IL1R2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This IL1R2 antibody is available for research use only.
Storage Conditions
Aliquot the IL1R2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the IL1R2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
IL1R2 antibody western blot analysis in WiDr lysate. Predicted molecular weight ~ 45 kDa.
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