VU 0360223
VU 0360223 is a potent metabotropic glutamate receptors (mGluR) negative allosteric modulator with an IC50 of 61 nM[1].
Product Specifications
CAS Number
[1274859-33-4]
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vu-0360223.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC(C2=CC=C(SC(C)=N3)C3=C2)=CC(F)=C1
Molecular Formula
C15H9FN2S
Molecular Weight
268.31
References & Citations
[1]Pomierny-Chamioło L, et al. Metabotropic glutamatergic receptors and their ligands in drug addiction. Pharmacol Ther. 2014 Jun;142 (3) :281-305.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR
Curated Selection
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