VU 0360223
Product Specifications
UNSPSC Description
VU 0360223 is a potent metabotropic glutamate receptors (mGluR) negative allosteric modulator with an IC50 of 61 nM[1].
Target Antigen
mGluR
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vu-0360223.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC(C2=CC=C(SC(C)=N3)C3=C2)=CC(F)=C1
Molecular Weight
268.31
References & Citations
[1]Pomierny-Chamioło L, et al. Metabotropic glutamatergic receptors and their ligands in drug addiction. Pharmacol Ther. 2014 Jun;142(3):281-305.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-103573/VU-0360223-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-103573/
Clinical Information
No Development Reported
CAS Number
1274859-33-4
Curated Selection
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