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JPC0323 Oleate

JPC0323 Oleate is a derivative of JPC0323. JPC0323 is a dual 5-HT2C/5-HT2A receptor positive allosteric modulator. JPC0323 has on-target properties, acceptable plasma exposure and brain penetration. JPC0323 can be used for the research of neurological disease[1].

Product Specifications

CAS Number

1612785-68-8

UNSPSC

12352211

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/jpc0323-oleate.html

Smiles

CCCCCCCC/C=C\CCCCCCCC(OCC(CO)(CO)NC(CCCCCCC/C=C\CCCCCCCC)=O)=O

Molecular Formula

C40H75NO5

Molecular Weight

650.03

References & Citations

[1]Chen J, et al. Discovery of Novel Oleamide Analogues as Brain-Penetrant Positive Allosteric Serotonin 5-HT2C Receptor and Dual 5-HT2C/5-HT2A Receptor Modulators. J Med Chem. 2023 Jul 27;66 (14) :9992-10009.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT2 Receptor

Frequently Asked Questions

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