MAP3K1 Recombinant Rabbit Monoclonal Antibody [PSH06-10]
The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. A disorder of sex development. Affected individuals have a 46,XY karyotype but present as phenotypically normal females.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
MAP3K1, MAPKKK1, MEKK, MEKK1
Swiss Prot
Q13233 Human, P53349 Mouse, Q62925 Rat
Cellular Locus
Cytoplasm, cytosol.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide within Human MAP3K1 aa 1413-1512.
Isotype
IgG
Clone
PSH06-10
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
Concentration
1 mg/mL
Dilution
WB: 1:2,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 165 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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