Quin C1

Quin C1 is a highly specific and potent agonist for formyl peptide receptor 2 (FPR2/ALX) . Quin-C1 significantly reduces the neutrophil and lymphocyte counts in BALF, diminishes expression of TNF-α, IL-1β, KC, and TGF-β1, and decreases collagen deposition in lung tissue. Quin C1 has the potential for the research of lung injury[1].

Product Specifications

CAS Number

[786706-21-6]

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Formyl Peptide Receptor (FPR)

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/quin-c1.html

Purity

98.47

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(OCCCC)C=C1)NN2C(C3=CC=C(OC)C=C3)NC4=CC=CC=C4C2=O

Molecular Formula

C26H27N3O4

Molecular Weight

445.51

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]He M, et al. Characterization of Quin-C1 for its anti-inflammatory property in a mouse model of bleomycin-induced lung injury. Acta Pharmacol Sin. 2011;32 (5) :601-610.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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