Contezolid acefosamil (sodium)
Product Specifications
UNSPSC Description
Contezolid acefosamil sodium (MRX-4), a new and orally active oxazolidinone, is an antibiotic in study for complicated skin and soft tissue infections (cSSTI) caused by resistant Gram-positive bacteria. Contezolid acefosamil sodium (MRX-4) markedly reduces potential for myelosuppression and monoamine oxidase inhibition (MAOI)[1][2].
Target Antigen
Antibiotic; Bacterial; Monoamine Oxidase
Type
Reference compound
Related Pathways
Anti-infection;Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/contezolid-acefosamil-sodium.html
Purity
95.19
Solubility
DMSO : 180 mg/mL (ultrasonic)
Smiles
FC(C(F)=C1N(C=C2)CCC2=O)=C(N(C(O3)=O)C[C@@H]3CN(C4=NOC=C4)[P](OC(C)=O)(O[Na])=O)C=C1F
Molecular Weight
552.33
References & Citations
[1]Junzhen Wu, et al. Evaluation of the Effect of Contezolid (MRX-I) on the Corrected QT Interval in a Randomized, Double-Blind, Placebo- and Positive-Controlled Crossover Study in Healthy Chinese Volunteers. Antimicrob Agents Chemother. 2020 May 21;64(6):e02158-19.|[2]Mikhail F Gordeev, et al. New potent antibacterial oxazolidinone (MRX-I) with an improved class safety profile. J Med Chem. 2014 Jun 12;57(11):4487-97.|[3]Carolyn Shoen, et al. In Vitro and In Vivo Activities of Contezolid (MRX-I) against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2018 Jul 27;62(8):e00493-18.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, stored under nitrogen
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-19915B/Contezolid-acefosamil-sodium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-19915B/Contezolid-acefosamil-sodium-SDS-MedChemExpress.pdf
Clinical Information
Phase 1
CAS Number
1807365-35-0
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6477755-01 0.1 mL
GGT1 (Gamma-glutamyltranspeptidase 1, GGT 1, GGT, CD224, D22S672, D22S732, Gamma-glutamyltransferase 1, GTG, MGC96892, MGC96904, MGC96963) (MaxLight 750)
Ask
View Details MBS6477755-02 5x 0.1 mL
GGT1 (Gamma-glutamyltranspeptidase 1, GGT 1, GGT, CD224, D22S672, D22S732, Gamma-glutamyltransferase 1, GTG, MGC96892, MGC96904, MGC96963) (MaxLight 750)
Ask
View Details 