Sphingolactone-24

Sphingolactone-24 (Sph-24) is a selective and irreversible neutral sphingomyelinase (nSMase) inhibitor. Sphingolactone-24 has the potential for the research of acute lung injury[1].

Product Specifications

CAS Number

[881177-99-7]

Product Name Alternative

Sph-24

UNSPSC

12352005

Target

Phospholipase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/sphingolactone-24.html

Smiles

C/C=C/C=C/C(N[C@H]([C@@]1([H])CC(C(O1)=O)CCCCCC)CO)=O

Molecular Formula

C18H29NO4

Molecular Weight

323.43

References & Citations

[1]Lin WC, et al. Inhibition of neutrophil apoptosis via sphingolipid signaling in acute lung injury. J Pharmacol Exp Ther. 2011 Oct;339 (1) :45-53.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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