Sphingolactone-24
Sphingolactone-24 (Sph-24) is a selective and irreversible neutral sphingomyelinase (nSMase) inhibitor. Sphingolactone-24 has the potential for the research of acute lung injury[1].
Product Specifications
CAS Number
[881177-99-7]
Product Name Alternative
Sph-24
UNSPSC
12352005
Target
Phospholipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sphingolactone-24.html
Smiles
C/C=C/C=C/C(N[C@H]([C@@]1([H])CC(C(O1)=O)CCCCCC)CO)=O
Molecular Formula
C18H29NO4
Molecular Weight
323.43
References & Citations
[1]Lin WC, et al. Inhibition of neutrophil apoptosis via sphingolipid signaling in acute lung injury. J Pharmacol Exp Ther. 2011 Oct;339 (1) :45-53.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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