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7,12-Diketolithocholic acid

7,12-Diketolithocholic acid (7,12-Diketo-LCA) is a bile acid, which can be produced in the host-gut microbial co-metabolism of the bile acid pool[1].

Product Specifications

CAS Number

[517-33-9]

Product Name Alternative

7,12-Dioxolithocholic acid; 3-Hydroxy-7,12-diketocholanoic acid; 7,12-Diketo-LCA

UNSPSC

12352211

Hazard Statement

H319

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/7-12-diketolithocholic-acid.html

Purity

99.93

Solubility

DMSO : 100 mg/mL

Smiles

O[C@@H](C[C@@](CC([C@@]1([H])[C@]2([H])CC[C@@H]([C@]23C)[C@H](C)CCC(O)=O)=O)4[H])CC[C@]4(C)[C@@]1([H])CC3=O

Molecular Formula

C24H36O5

Molecular Weight

404.54

Precautions

H319

References & Citations

[1]Lan K, et al., Key Role for the 12-Hydroxy Group in the Negative Ion Fragmentation of Unconjugated C24 Bile Acids. Anal Chem. 2016 Jul 19;88 (14) :7041-8.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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