BC-11 (hydrobromide)
BC-11 hydrobromide is a selective TMPRSS2 inhibitor (TMPRSS2 is a key host cellular factor for viral entry and SARS-CoV-2 pathogenesis), and a selective urokinase (uPA) inhibitor (IC50=8.2 μM) . BC-11 hydrobromide is cytotoxic to triple-negative MDA-MB231 breast cancer cells. BC-11 hydrobromide is used in research on viral infections and cancer[1][2][3].
Product Specifications
CAS Number
443776-49-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PAI-1; SARS-CoV; Ser/Thr Protease
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/bc-11-hydrobromide.html
Purity
99.0
Solubility
DMSO : 125 mg/mL (ultrasonic) |H2O : 25 mg/mL (ultrasonic)
Smiles
NC(SCC1=CC=C(B(O)O)C=C1)=N.[H]Br
Molecular Formula
C8H12BBrN2O2S
Molecular Weight
290.98
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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