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Valosin-Containing Protein Recombinant Protein

Product Specifications

Background

Valosin-Containing Protein (VCP) is a nuclear protein that belongs to the AAA ATPase family. VCP is a putative ATP-binding protein involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. It is necessary for the fragmentation of Golgi stacks during mitosis and their reassembly after mitosis. VCP has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation. VCP participates in the formation of the transitional endoplasmic reticulum (tER) and regulates E3 ubiquitin-protein ligase activity of RNF19A.

CAS Number

9000-83-3

NCBI Gene ID

7415

Swiss Prot

P55072

Accession Number

P55072

Tag

C-6 His tag

Type

Recombinant Proteins

Source

E. coli

Field of Research

Neuroscience, Obesity, Signal Transduction

Buffer

Supplied as a 0.2 um filtered solution of 50mM TrisHCl, pH8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

Shipping Conditions

Dry Ice

Calculated Molecular Weight

66.4 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Valosin containing protein

NCBI Organism

Homo sapiens

Other Product Names

Transitional Endoplasmic Reticulum ATPase, TER ATPase, 15S Mg (2+) -ATPase p97 Subunit, Valosin-Containing Protein, VCP

Species

Human

Physical Properties

Liquid

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