TrkB Recombinant Protein
Product Specifications
Background
The TRK Family of Tyrosine Kinase Receptor consists of 3 members: TrkA, TrkB and TrkC. The three TRK family proteins have different ligand specificities. They connect to different neurotrophins, including NGF, BDNF, NT-3NT-4/5. TRKA binds NGF, TRKB binds BDNF and NT-3, TRKC binds NT-4/5. At the protein sequence level, human and rat TRKB have greater than 90% sequence identity and the proteins exbihit cross-species activity. TRKB is primarily expressed in the nervous system and it also expression in a wide variety of tissues with low levels.
NCBI Gene ID
4915
Swiss Prot
Q16620
Accession Number
Q16620
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Neuroscience, Obesity, Signal Transduction
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=91-458
Calculated Molecular Weight
45.25 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Neurotrophic receptor tyrosine kinase 2
NCBI Organism
Homo sapiens
Other Product Names
BDNF/NT-3 Growth Factors Receptor, GP145-TrkB, Trk-B, Neurotrophic Tyrosine Kinase Receptor Type 2, TrkB Tyrosine Kinase, Tropomyosin-Related Kinase B, NTRK2, TRKB
Species
Human
Protein ID
767928039
Physical Properties
Lyophilized
CAS Number
9000-83-3
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