TrkB Recombinant Protein

Product Specifications

Background

The TRK Family of Tyrosine Kinase Receptor consists of 3 members: TrkA, TrkB and TrkC. The three TRK family proteins have different ligand specificities. They connect to different neurotrophins, including NGF, BDNF, NT-3NT-4/5. TRKA binds NGF, TRKB binds BDNF and NT-3, TRKC binds NT-4/5. At the protein sequence level, human and rat TRKB have greater than 90% sequence identity and the proteins exbihit cross-species activity. TRKB is primarily expressed in the nervous system and it also expression in a wide variety of tissues with low levels.

CAS Number

9000-83-3

NCBI Gene ID

4915

Swiss Prot

Q16620

Accession Number

Q16620

Tag

C-6 His tag

Type

Recombinant Proteins

Source

Human Cells

Field of Research

Neuroscience, Obesity, Signal Transduction

Buffer

Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Shipping Conditions

Room Temp

Calculated Molecular Weight

45.25 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Neurotrophic receptor tyrosine kinase 2

NCBI Organism

Homo sapiens

Other Product Names

BDNF/NT-3 Growth Factors Receptor, GP145-TrkB, Trk-B, Neurotrophic Tyrosine Kinase Receptor Type 2, TrkB Tyrosine Kinase, Tropomyosin-Related Kinase B, NTRK2, TRKB