PPC-DC Recombinant Protein
Product Specifications
Background
Phosphopantothenoylcysteine Decarboxylase (PPC-DC) is an essential enzyme in the biosynthesis ofCoenzyme A and catalyzes the decarboxylation of PPC to Phosphopantetheine. PPC-DC catalyzes the decarboxylation of the Cysteine moiety of 4-Phosphopantothenoylcysteine (PPC) to form 4-Phosphopantetheine (PPantSH), this reaction forms part of the biosynthesis of Coenzyme A. The enzyme is a member of the larger family of Cysteine Decarboxylases including the Lantibiotic-Biosynthesizing enzymes EpiD and MrsD, all of which use a tightly bound Flavin cofactor to oxidize the Thiol moiety of the substrate to a Thioaldehyde.
CAS Number
9000-83-3
NCBI Gene ID
60490
Swiss Prot
Q96CD2
Accession Number
Q96CD2
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Obesity, Signal Transduction
Buffer
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 50mM NaCl, 1mM DTT, 10% Glycerol, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
24.6 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Phosphopantothenoylcysteine decarboxylase
NCBI Organism
Homo sapiens
Other Product Names
Phosphopantothenoylcysteine Decarboxylase, PPC-DC, PPCDC, COAC
Species
Human
Physical Properties
Liquid
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