Recombinant human DIMT1 protein
DIMT1 (DIM1 dimethyladenosine transferase 1 homolog) belongs to the methyltransferase superfamily. This enzyme is specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. It functions to dimethylate adjacent adenosines on the conserved hairpin loop of 18S rRNA in the 40S particle. DIMT1L is localized to the nucleolus. Recombinant human DIMT1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
DIM1 dimethyladenosine transferase 1 homolog, DIM1, DIMT1L, HSA9761, HuSSY5
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.25 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
37.5 kDa (334aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Scherl A., et al. (2002) Mol. Biol. Cell 13:4100-4109; ; Saltman, et al. (1993) Genomics 16:726-732.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 30% glycerol, 2mM DTT, 200 mM NaCl, 2mM EDTA
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_055288
Uniprot Accession Number
Q9UNQ2
Species
Human
AA Sequence
Frequently Asked Questions
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