Carbonic anhydrase 14 Recombinant Protein
Product Specifications
Background
Mouse Ca14, also known as Carbonic anhydrase 14, is a member of large family of zinc metalloenzymes .It could catalyze reversible hydration of carbon dioxide. The reaction is fundamental to many processes such as respiration, renal tubular acidification and bone resorption. Fifteen CA isoforms have been reported so far. They have different patterns of tissue-specific expression and physiologic roles. Some CAs may serve as markers for tumors and hypoxia. CA XIV is a polypeptide consisting of an extracellular N-terminal catalytic domain, a membrane-spanning segment and a short intracellular C- terminal segment with several potential phosphorylation sites. A subset of CAs lack CA activity due to point mutations but retain esterase function. CA14 is widely expressed in the central nervous system
CAS Number
9000-83-3
NCBI Gene ID
23831
Swiss Prot
Q9WVT6
Accession Number
Q9WVT6
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cell Cycle, Obesity, Neuroscience, Signal Transduction, Cancer
Buffer
Supplied as a 0.2 um filtered solution of 20mM Tris,150mM NaCl, pH8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
32.3 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Carbonic anhydrase 14
NCBI Organism
Mus musculus
Other Product Names
Carbonic Anhydrase 14, Carbonate Dehydratase XIV, Carbonic Anhydrase XIV, CA-XIV, CA14
Species
Mouse
Physical Properties
Liquid
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