Tigloyl-CoA
Tigloyl-CoA (Tiglyl-coenzyme A) is an intermediate product of isoleucine metabolism. Tigloyl-CoA is an inhibitor of N-acetylglutamate synthetase[1].
Product Specifications
CAS Number
6247-62-7
Product Name Alternative
Tiglyl-coenzyme A
UNSPSC
12352204
Target
Endogenous Metabolite
Type
Enzyme
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/tigloyl-coa.html
Solubility
10 mM in DMSO
Smiles
NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](OP(O)(O)=O)[C@@H](COP(O)(OP(O)(OCC(C)([C@H](C(NCCC(NCCSC(/C(C)=C/C)=O)=O)=O)O)C)=O)=O)O3
Molecular Formula
C26H42N7O17P3S
Molecular Weight
849.63
References & Citations
[1]Coude FX, et al. Inhibition by propionyl-coenzyme A of N-acetylglutamate synthetase in rat liver mitochondria. A possible explanation for hyperammonemia in propionic and methylmalonic acidemia. J Clin Invest. 1979 Dec;64 (6) :1544-51.
Shipping Conditions
Room temperature
Scientific Category
Enzyme
Clinical Information
No Development Reported
Frequently Asked Questions
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