LZTS1 / FEZ1 Rabbit Polyclonal Antibody
This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Abbreviation
LZTS1, FEZ1
Swiss Prot
Q9Y250 Human, P60853 Mouse, Q8CFC9 Rat
Cellular Locus
Cytoplasm, Cell membrane, Cell projection, dendritic spine, Postsynaptic density, Synapse.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within human LZTS1 aa 201-596 / 596.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
Jurkat cell lysate, 293T cell lysate, human brain tissue lysate, mouse brain tissue lysate, rat brain tissue lysate, Jurkat, human brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IF-Cell: 1:100 ;IHC-P: 1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 67 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No
Frequently Asked Questions
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