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E3 ligase Ligand 42

E3 ligase Ligand 42 is an E3 ubiquitin ligase ligand. E3 ligase Ligand 42 can be connected to the target protein ligand through a linker and can be used to synthesize PROTAC AR Degrader-6. PROTAC can induce ubiquitination degradation of cancer-promoting proteins[1].

Product Specifications

CAS Number

2753651-18-0

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Ligands for E3 Ligase

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/e3-ligase-ligand-42.html

Smiles

O=C(C(N(N=CC1=C2C=CC(F)=C1)C2=O)CC3)NC3=O

Molecular Formula

C13H10FN3O3

Molecular Weight

275.24

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Hongfu Lu, et al. Phthalazinone compound, and preparation method therefor and medical use thereof. WO2021249534A1. 2021-06-11

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Frequently Asked Questions

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