FMIFL

FMIFL is an FPR1 agonist. fMIFL can activate several signaling pathways responsible for various neutrophil functions, such as adhesion, chemotaxis, secretion of granule exocytosis, and the production of superoxide anions. fMIFL can be used in research on bacterial infections and tissue damage[1].

Product Specifications

CAS Number

[112275-26-0]

UNSPSC

12352209

Target

Bacterial; Formyl Peptide Receptor (FPR)

Type

Peptides

Related Pathways

Anti-infection; GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/fmifl.html

Purity

99.79

Solubility

H2O : 7.1 mg/mL (ultrasonic; warming; adjust pH to 8 with NH4OH)

Smiles

O=C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)[C@H](CCSC)NC=O

Molecular Formula

C27H42N4O6S

Molecular Weight

550.71

References & Citations

[1]Dalpiaz A, et al. Studies on human neutrophil biological functions by means of formyl-peptide receptor agonists and antagonists. Curr Drug Targets Immune Endocr Metabol Disord. 2003 Mar;3 (1) :33-42.