CL4H6
CL4H6 is a pH-sensitive cationic lipid. CL4H6 is the main component of lipid nanoparticles (LNPs), which can be used to target and deliver siRNA, and induces a potent gene-silencing response[1][2].
Product Specifications
CAS Number
[2256087-35-9]
UNSPSC
12352211
Target
Liposome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cl4h6.html
Purity
98.32
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCCN(CCC)CCCCC(CCCCCCOC(CCCCCCC/C=C\CCCCCCCC)=O)(O)CCCCCCOC(CCCCCCC/C=C\CCCCCCCC)=O
Molecular Formula
C59H113NO5
Molecular Weight
916.53
References & Citations
[1]Amisha Sanghani, et al. Novel PEGylated Lipid Nanoparticles Have a High Encapsulation Efficiency and Effectively Deliver MRTF-B siRNA in Conjunctival Fibroblasts. Pharmaceutics. 2021 Mar 13;13 (3) :382.|[2]Nour Shobaki, et al. Manipulating the function of tumor-associated macrophages by siRNA-loaded lipid nanoparticles for cancer immunotherapy. J Control Release. 2020 Sep 10;325:235-248.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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