BEC

BEC, an arginine analogue, is a slow-binding competitive inhibitor of the binuclear manganese metalloenzyme arginase. BEC enhances substrate flux to NO synthase, thereby enhancing NO-dependent smooth muscle relaxation in the corpus cavernosum, and enhances penile erection[1].

Product Specifications

CAS Number

[63107-40-4]

UNSPSC

12352211

Hazard Statement

H302-H315-H319

Target

Arginase

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/bec.html

Solubility

10 mM in DMSO

Smiles

OB(O)CCSC[C@H](N)C(O)=O

Molecular Formula

C5H12BNO4S

Molecular Weight

193.03

Precautions

P264-P270-P280-P302+P352-P330-P362+P364-P501

References & Citations

[1]Kim NN, et al. Probing erectile function: S- (2-boronoethyl) -L-cysteine binds to arginase as a transition state analogue and enhances smooth muscle relaxation in human penile corpus cavernosum. Biochemistry. 2001 Mar 6;40 (9) :2678-88.