BEC
BEC, an arginine analogue, is a slow-binding competitive inhibitor of the binuclear manganese metalloenzyme arginase. BEC enhances substrate flux to NO synthase, thereby enhancing NO-dependent smooth muscle relaxation in the corpus cavernosum, and enhances penile erection[1].
Product Specifications
CAS Number
63107-40-4
UNSPSC
12352211
Hazard Statement
H302-H315-H319
Target
Arginase
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/bec.html
Solubility
10 mM in DMSO
Smiles
OB(O)CCSC[C@H](N)C(O)=O
Molecular Formula
C5H12BNO4S
Molecular Weight
193.03
Precautions
P264-P270-P280-P302+P352-P330-P362+P364-P501
References & Citations
[1]Kim NN, et al. Probing erectile function: S- (2-boronoethyl) -L-cysteine binds to arginase as a transition state analogue and enhances smooth muscle relaxation in human penile corpus cavernosum. Biochemistry. 2001 Mar 6;40 (9) :2678-88.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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