CYP17A1 rabbit pAb
Cytochrome P450 family 17 subfamily A member 1 (CYP17A1) Homo sapiens This gene encodes a member of the Cytochrome P450 superfamily of enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17, 20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17, 20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Product Name Alternative
UniProt
P05093
Swiss Prot
P05093
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 17A1. AA range:221-270
Target
CYP17A1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Buffer
-20°C/1 year
Molecular Weight
50kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
50kD
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane . Microsome membrane .
Other Product Names
Gene ID (Human)
1586
Available Sizes
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