Diazoxide (Standard)

Diazoxide (Standard) is the analytical standard of Diazoxide. This product is intended for research and analytical applications. Diazoxide (Sch-6783) is an ATP-sensitive potassium channel activator, has the potential for hyperinsulinism treatment.

Product Specifications

CAS Number

[364-98-7]

Product Name Alternative

Sch-6783 (Standard) ; SRG-95213 (Standard)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335, H361

Target

Autophagy; Potassium Channel; Reference Standards

Type

Reference Standards

Related Pathways

Autophagy; Membrane Transporter/Ion Channel; Others

Applications

Cancer-programmed cell death

Field of Research

Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/diazoxide-standard.html

Purity

99.78

Smiles

CC(NC1=CC=C(Cl)C=C12)=NS2(=O)=O

Molecular Formula

C8H7ClN2O2S

Molecular Weight

230.67

Precautions

H302, H315, H319, H335, H361

References & Citations

[1]Coetzee WA, et al. Multiplicity of effectors of the cardioprotective agent, diazoxide. Pharmacol Ther. 2013 Nov;140 (2) :167-75.|[2]Virgili N, et al. K (ATP) channel opener diazoxide prevents neurodegeneration: a new mechanism of action viaantioxidative pathway activation. PLoS One. 2013 Sep 11;8 (9) :e75189.|[3]Wu H, et al. Diazoxide Attenuates Postresuscitation Brain Injury in a Rat Model of Asphyxial Cardiac Arrest by Opening Mitochondrial ATP-Sensitive Potassium Channels. Biomed Res Int. 2016;2016:1253842.|[4]Chowdhury UR, et al. ATP-sensitive potassium (K (ATP) ) channel openers diazoxide and nicorandil lower intraocular pressure in vivo. Invest Ophthalmol Vis Sci. 2013 Jul 22;54 (7) :4892-9.