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Xanthine oxidoreductase-IN-1

Xanthine oxidoreductase-IN-1 (Compound Ie) is a xanthine oxidoreductase (XOR) inhibitor with the IC50 of 8.0 nM. Xanthine oxidoreductase-IN-1 shows hypouricemic effects in mice[1].

Product Specifications

CAS Number

[2396612-00-1]

UNSPSC

12352005

Target

Xanthine Oxidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/xanthine-oxidoreductase-in-1.html

Solubility

10 mM in DMSO

Smiles

N#CC1=C(C=CC(N2C=NC(C(O)=O)=C2)=C1)N3CCCCCCC3

Molecular Formula

C18H20N4O2

Molecular Weight

324.38

References & Citations

[1]Haiyan Zhou, et al. Synthesis and bioevaluation of 1-phenylimidazole-4-carboxylic acid derivatives as novel xanthine oxidoreductase inhibitors. Eur J Med Chem. 2020 Jan 15;186:111883.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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