Mono-(2-ethylhexyl) phthalate
Product Specifications
UNSPSC Description
Mono-(2-ethylhexyl) phthalate (MEHP) is a major bioactive metabolite of diethylhexyl phthalate (DEHP). Mono-(2-ethylhexyl) phthalate can promote fatty acid synthesis in hepatocytes by regulating the expression of relevant genes and proteins, contributing to non-alcoholic fatty liver disease (NAFLD)[1].
Target Antigen
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/mono-2-ethylhexyl-phthalate.html
Purity
97.08
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(O)C1=CC=CC=C1C(OCC(CC)CCCC)=O
Molecular Weight
278.348
References & Citations
[1]Bai J, et al. Mono-2-ethylhexyl phthalate induces the expression of genes involved in fatty acid synthesis in HepG2 cells. Environ Toxicol Pharmacol. 2019 Jul;69:104-111.|[2]Tomita I, et al. Fetotoxic effects of mono-2-ethylhexyl phthalate (MEHP) in mice. Environ Health Perspect. 1986 Mar;65:249-54.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W018392/Mono-2-ethylhexyl-phthalate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W018392/Mono-2-ethylhexyl-phthalate-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
4376-20-9
Available Sizes
Curated Selection
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