MLL5 Antibody (N-term) [APR03921G]

Product Specifications

Background

Tissue Location: Widely expressed in both adult and fetal tissues (PubMed:12101424, PubMed:23958951) . Highest levels of expression observed in fetal thymus and kidney and in adult hematopoietic tissues, jejunum and cerebellum (PubMed:12101424, PubMed:23958951) . Isoform NKp44L: Not detected on circulating cells from healthy individuals, but is expressed on a large panel of tumor and transformed cells (PubMed:23958951) .

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MLL5 Antibody (N-term) [APR03921G].

Synonyms

Histone-lysine N-methyltransferase 2E, Lysine N-methyltransferase 2E, Myeloid/lymphoid or mixed-lineage leukemia protein 5, KMT2E, MLL5

Gene Name

KMT2E

Gene ID

55904

UniProt

Q8IZD2

Chromosomal Location

Chromosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus speckle. Note=Absent from the nucleolus (PubMed:14718661) . Localizes to chromosome during interphase and to centrosomes during mitosis (PubMed:23798402) . Dissociation from mitotic chromosome is likely due to histone H3 phosphorylation on 'Thr-3' and 'Thr-6' (PubMed:23798402) . [Isoform NKp44L]: Cytoplasm. Cell membrane; Peripheral membrane protein

Applications

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.