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SPAK Antibody (Center) [APR06998G]

Product Specifications

Background

Tissue Location: Predominantly expressed in brain and pancreas followed by heart, lung, kidney, skeletal muscle, liver, placenta and testis

Synonyms

STE20/SPS1-related proline-alanine-rich protein kinase, Ste-20-related kinase, DCHT, Serine/threonine-protein kinase 39, STK39, SPAK

Gene Name

STK39

Gene ID

27347

UniProt

Q9UEW8

Chromosomal Location

Cytoplasm. Nucleus. Note=Nucleus when caspase-cleaved.

Applications

WB, IHC-P

Dilution

WB--1:1000 IHC-P--1:100~500

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Function

May act as a mediator of stress-activated signals. Mediates the inhibition of SLC4A4, SLC26A6 as well as CFTR activities by the WNK scaffolds, probably through phosphorylation. Phosphorylates RELT.

Molecular Weight

59474

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SPAK Antibody (Center) [APR06998G].

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=27347

Uniprot URL

https://www.uniprot.org/uniprot/Q9UEW8

Available Sizes

Curated Selection

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