Human Pancreatic Trypsin

<strong>Human Pancreatic Trypsin</strong>_x000D_ <strong>Catalog number:</strong> B2019119_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 0.1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −20°C_x000D_ <strong>Keywords:</strong> Pancreatic Trypsin, Human_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Resovi A, Persichitti P, Brunelli L, Minoli L, Borsotti P, Garattini G, Tironi M, Dugnani E, Redegalli M, De Simone G, Pastorelli R, Bani MR, Piemonti L, Mosher DF, Giavazzi R, Taraboletti G, Belotti D. Fibronectin fragments generated by pancreatic trypsin act as endogenous inhibitors of pancreatic tumor growth J Exp Clin Cancer Res. 2023 Aug 9;42(1):201._x000D_ 2: Lindstad RI, Sylte I, Mikalsen SO, Seglen PO, Berg E, Winberg JO. Pancreatic trypsin activates human promatrix metalloproteinase-2 J Mol Biol. 2005 Jul 22;350(4):682-98._x000D_ 3: Saluja A, Dudeja V, Dawra R, Sah RP. Early Intra-Acinar Events in Pathogenesis of Pancreatitis Gastroenterology. 2019 May;156(7):1979-1993._x000D_ 4: HAVERBACK BJ, DYCE B, BUNDY H, EDMONDSON HA. Trypsin, trypsinogen and trypsin inhibitor in human pancreatic juice Am J Med. 1960 Sep;29:421-33._x000D_ 5: Sahin-Tóth M. Human mesotrypsin defies natural trypsin inhibitors: from passive resistance to active destruction Protein Pept Lett. 2005 Jul;12(5):457-64._x000D_ 6: Weiss FU, Laemmerhirt F, Aghdassi A, Lerch MM. New horizons in pancreatic genetics Curr Opin Gastroenterol. 2020 Sep;36(5):437-442._x000D_ 7: Morales Granda NC, Toldi V, Miczi M, Lassoued M, Szabó A. Inhibition of mouse trypsin isoforms by SPINK1 and effect of human pancreatitis-associated mutations Pancreatology. 2023 Jun;23(4):358-366._x000D_ 8: Tan JH, Cao RC, Zhou L, Zhou ZT, Chen HJ, Xu J, Chen XM, Jin YC, Lin JY, Zeng JL, Li SJ, Luo M, Hu GD, Yang XB, Jin J, Zhang GW. ATF6 aggravates acinar cell apoptosis and injury by regulating p53/AIFM2 transcription in Severe Acute Pancreatitis Theranostics. 2020 Jul 9;10(18):8298-8314._x000D_ 9: Wang YC, Mao XT, Sun C, Wang YH, Zheng YZ, Xiong SH, Liu MY, Mao SH, Wang QW, Ma GX, Wu D, Li ZS, Chen JM, Zou WB, Liao Z. Pancreas-directed AAV8-hSPINK1 gene therapy safely and effectively protects against pancreatitis in mice Gut. 2024 Jun 6;73(7):1142-1155._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/31419436">10: Huang H, Swidnicka-Siergiejko AK, Daniluk J, Gaiser S, Yao Y, Peng L, Zhang Y, Liu Y, Dong M, Zhan X, Wang H, Bi Y, Li Z, Ji B, Logsdon CD. Transgenic Expression of PRSS1(R122H) Sensitizes Mice to Pancreatitis Gastroenterology. 2020 Mar;158(4):1072-1082.e7. </a>_x000D_ _x000D_ <strong>Products Related to Human Pancreatic Trypsin can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>