MurA-IN-1
MurA-IN-1 (compound 1a) is a PTPRR inhibitor, with IC50 values of 0.23 μM, 0.8 μM, 0.75 μM and 0.09 μM for PTP1B, PTPN5, PTPN7 and PTPRR, respectively[1]. (A family of human MAPK-specific protein tyrosine phosphatases)
Product Specifications
CAS Number
[354815-90-0]
UNSPSC
12352005
Hazard Statement
H301
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/mura-in-1.html
Concentration
10mM
Purity
99.32
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1NC2=C(C=CC=C2)C3C1CC=C3)O
Molecular Formula
C13H13NO2
Molecular Weight
215.25
Precautions
H301
References & Citations
[1]Jeyanthy Eswaran, et al. Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases. Biochem J. 2006 May 1;395 (3) :483-91.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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