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MurA-IN-1

MurA-IN-1 (compound 1a) is a PTPRR inhibitor, with IC50 values of 0.23 μM, 0.8 μM, 0.75 μM and 0.09 μM for PTP1B, PTPN5, PTPN7 and PTPRR, respectively[1]. (A family of human MAPK-specific protein tyrosine phosphatases)

Product Specifications

CAS Number

[354815-90-0]

UNSPSC

12352005

Hazard Statement

H301

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/mura-in-1.html

Concentration

10mM

Purity

99.32

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C1NC2=C(C=CC=C2)C3C1CC=C3)O

Molecular Formula

C13H13NO2

Molecular Weight

215.25

Precautions

H301

References & Citations

[1]Jeyanthy Eswaran, et al. Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases. Biochem J. 2006 May 1;395 (3) :483-91.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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