L-Valine-1-13C

L-Valine-1-13C ((S) -Valine-1-13C) is the 13C-labeled L-Valine (HY-N0717) . L-Valine ((S) -Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase[1][2][3].

Product Specifications

CAS Number

[81201-85-6]

Product Name Alternative

(S) -Valine-1-13C

UNSPSC

12352211

Target

Akt; Arginase; Bacterial; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; Others; PI3K/Akt/mTOR

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/l-valine-1-13c.html

Purity

99.75

Solubility

10 mM in DMSO|H2O : 20mg/mL (ultrasonic)

Smiles

N[C@@H](C(C)C)[13C](O)=O

Molecular Formula

C4 13CH11NO2

Molecular Weight

118.14

References & Citations

[1]Zhang BH, et al., L-valine, an antialgal amino acid from Streptomyces jiujiangensis JXJ 0074 (T) . Appl Microbiol Biotechnol. 2016 May;100 (10) :4627-36.|[2]Chen XH, et al., Exogenous l-Valine Promotes Phagocytosis to Kill Multidrug-Resistant Bacterial Pathogens. Front Immunol. 2017 Mar 6;8:207.|[3]K Kirubavathi, et al. Synthesis, growth, structural, spectroscopic and optical studies of a new semiorganic nonlinear optical crystal: L-valine hydrochloride. Spectrochim Acta A Mol Biomol Spectrosc. 2008 Apr;69 (4) :1283-6.