Human BCHE / Butyrylcholinesterase Protein, His Tag (active enzyme)
Human BCHE, His Tag (BHE-H52H3) is expressed from human 293 cells (HEK293) . It contains AA Glu 29 - Leu 602 (Accession # P06276-1) .
Product Specifications
Background
BCHE (also known as Butyrylcholinesterase, pseudocholinesterase, plasma cholinesterase, or BuChE) is a nonspecific cholinesterase enzyme that hydrolyzes many different choline esters. Both acetylcholinesterase and butyrylcholinesterase represent therapeutic targets for ameliorating the cholinergic deficit considered to be responsible for the declines in cognitive, behavioral and global functioning characteristic of Alzheimer's disease (AD) .
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 67.0 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P06276-1
Expression Region
Glu 29 - Leu 602
Host
HEK293
Target
BCHE
Conjugation
Unconjugated
Tag
C-10xHis
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Format
Powder
Buffer
50 mM Tris, 150 mM NaCl, pH8.0
Additives
Trehalose
Molecular Weight
67.0 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
500ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/BHE-H52H3.pdf
Species
Human
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