MAC-0547630
MAC-0547630 is a potent inhibitor of undecaprenyl diphosphate synthase (UppS), with IC50s of 0.05 μM and 1.6 μM for UppSBS and UppSBA, respectively. MAC-0547630 is active against B. subtilis in vitro (MIC 0.1 ng/mL) [1].
Product Specifications
CAS Number
950386-41-1
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mac-0547630.html
Smiles
FC1=CC=C(C2=C(N=C(C)C=C3N4CCCCCC4)N3N=C2)C=C1
Molecular Formula
C19H21FN4
Molecular Weight
324.40
References & Citations
[1]Tomasz L Czarny, et al. A Small-Molecule Screening Platform for the Discovery of Inhibitors of Undecaprenyl Diphosphate Synthase. ACS Infect Dis. 2016 Jul 8;2 (7) :489-99.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PKSH033135-01 10 µg
Recombinant Human TFIIB/GTF2B Protein (GST Tag)
Sign In for Pricing
View Details PKSH033135-02 50 µg
Recombinant Human TFIIB/GTF2B Protein (GST Tag)
Sign In for Pricing
View Details 