Recombinant Human TFIIB/GTF2B Protein (GST Tag)
Product Specifications
Background
Transcription Initiation Factor IIB (TFIIB) is an essential factor for transcription by RNA Polymerase II. TFIIB localizes to the nucleus where it forms a complex (the DAB complex) with transcription factor IID and IIA. TFIIB plays a role as a bridge between IID, which initially recognizes the promoter sequence, and RNA polymerase II. TFIIB is involved in the selection of transcription start site.
Abbreviation
TFIIB; GTF2B
Synonyms
GTF2B; General Transcription Factor TFIIB; S300-II; TF2B; TFIIB; Transcription Initiation Factor IIB
UniProt
Q00403
Accession Number
Q00403
Expression System
E.coli
Tag
N-GST
Sequence
Met 1-Leu316
Field of Research
Epigenetics and nuclear signal
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 80 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
61.6 kDa
Observed Molecular Weight
62 kDa
Species
Human
Available Sizes
Frequently Asked Questions
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