10074-A4

10074-A4 is a c-Myc inhibitor. 10074-A4 could bind to c-Myc370-409 at different sites along the peptide chain. 10074-A4 has anticancer effects[1][2].

Product Specifications

CAS Number

[312631-87-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

C-Myc

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/10074-a4.html

Purity

98.22

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(SCC1=O)N1CC(CN2C3=C(C=C(C=C3)Cl)C4=C2C=CC(Cl)=C4)O

Molecular Formula

C18H14Cl2N2O3S

Molecular Weight

409.29

Precautions

H302, H315, H319

References & Citations

[1]Chen Yu, et al. Structure-based Inhibitor Design for the Intrinsically Disordered Protein c-Myc. Sci Rep. 2016 Mar 2;6:22298.|[2]Fan Jin, et al. Ligand clouds around protein clouds: a scenario of ligand binding with intrinsically disordered proteins. PLoS Comput Biol. 2013;9 (10) :e1003249.