NPPB antibody
Product Specifications
Background
NPPB, also known as B-type natriuretic peptide (BNP), is a cardiac hormone that is secreted mainly in the ventricles in response to increased wall stress. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. BNP is a marker of systolic and diastolic dysfunction and a strong predictor of mortality in heart failure patients.
Synonyms
Natriuretic peptides B|Brain natriuretic factor prohormone (preproBNP, proBNP)|Gamma-brain natriuretic peptide|Iso-ANP|NT-proBNP Alternative names: NT-pro-BNP|NT-proBNP(1-76)|proBNP(3-108)|Brain natriuretic peptide 32 (BNP(1-32), BNP-32) Alternative names: Brain natriuretic peptide (BNP)|BNP(1-30)|BNP(1-29)|BNP(1-28)|BNP(2-31)|BNP(3-32) Alternative names: des-SerPro-BNP|proBNP(79-108)|BNP(3-30)|BNP(3-29)|Brain natriuretic peptide 29 (BNP(4-32))|BNP(4-31)|BNP(4-30)|BNP(4-29)|BNP(4-27)|BNP(5-32)|BNP(5-31)|BNP(5-29)|NPPB
Gene ID
4879
UniProt
P16860
Host
Rabbit
Reactivity
Human
Immunogen
natriuretic peptide precursor B
Target
NPPB
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC
Field of Research
Stem Cells, Cardiovascular
Purification
Immunogen affinity purified
Dilution
IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
15 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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