SCN5A antibody

This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na (+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant Na (+) channel isoform. This channel is responsible for the initial upstroke of the action potential. Channel inactivation is regulated by intracellular calcium levels.

Sodium channel protein type 5 subunit alpha|Sodium channel protein cardiac muscle subunit alpha|Sodium channel protein type V subunit alpha|Voltage-gated sodium channel subunit alpha Nav1.5|hH1|SCN5A