SCN10A antibody
Product Specifications
Background
Tetrodotoxin-resistant channel that mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. Plays a role in neuropathic pain mechanisms.
Synonyms
Sodium channel protein type 10 subunit alpha|Peripheral nerve sodium channel 3 (PN3, hPN3) |Sodium channel protein type X subunit alpha|Voltage-gated sodium channel subunit alpha Nav1.8|SCN10A
Gene ID
6336
UniProt
Q9Y5Y9
Host
Rabbit
Reactivity
Human
Immunogen
Sodium channel, voltage-gated, type X, alpha subunit
Target
SCN10A
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IF
Field of Research
Neuroscience
Purification
Immunogen affinity purified
Dilution
IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IF
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