SCD antibody
Product Specifications
Background
Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates(PubMed:15907797, PubMed:18765284). Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA(PubMed:15907797, PubMed:18765284). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids(PubMed:15610069). Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation(By similarity). Plays an important role in body energy homeostasis(By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides(By similarity).
Synonyms
Stearoyl-CoA desaturase (hSCD1)|Acyl-CoA desaturase|Delta(9)-desaturase (Delta-9 desaturase)|Fatty acid desaturase|SCD|FADS5|SCD1|SCDOS
Gene ID
6319
UniProt
O00767
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
stearoyl-CoA desaturase(delta-9-desaturase)
Target
SCD
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
40 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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