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SCD antibody

Product Specifications

Background

Stearyl-CoA desaturase that utilizes O (2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates (PubMed:15907797, PubMed:18765284) . Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:15907797, PubMed:18765284) . Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids (PubMed:15610069) . Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity) . Plays an important role in body energy homeostasis (By similarity) . Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity) .

Synonyms

Stearoyl-CoA desaturase (hSCD1) |Acyl-CoA desaturase|Delta (9) -desaturase (Delta-9 desaturase) |Fatty acid desaturase|SCD|FADS5|SCD1|SCDOS

Gene ID

6319

UniProt

O00767

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Stearoyl-CoA desaturase (delta-9-desaturase)

Target

SCD

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

40 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

Immunogen Sequence

Peptide

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