S100A12 antibody
Product Specifications
Background
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.
Synonyms
Protein S100-A12|CGRP|Calcium-binding protein in amniotic fluid 1 (CAAF1) |Calgranulin-C (CAGC) |Extracellular newly identified RAGE-binding protein (EN-RAGE) |Migration inhibitory factor-related protein 6 (MRP-6, p6) |Neutrophil S100 protein|S100 calcium-binding protein A12|Calcitermin|S100A12
Gene ID
6283
UniProt
P80511
Host
Rabbit
Reactivity
Human
Immunogen
S100 calcium binding protein A12
Target
S100A12
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Immunology, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
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