NFAM1 antibody
Product Specifications
Background
May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking.
Synonyms
NFAT activation molecule 1|Calcineurin/NFAT-activating ITAM-containing protein|NFAT-activating protein with ITAM motif 1|NFAM1|CNAIP
Gene ID
150372
UniProt
Q8NET5
Host
Rabbit
Reactivity
Human
Immunogen
NFAT activating protein with ITAM motif 1
Target
NFAM1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC
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