NEK3 antibody
Product Specifications
Background
Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin-mediated phosphorylation of PXN and VAV2. Implicated in prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2.
Synonyms
Serine/threonine-protein kinase Nek3|HSPK 36|Never in mitosis A-related kinase 3 (NimA-related protein kinase 3)|NEK3
Gene ID
4752
UniProt
P51956
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
NIMA(never in mitosis gene a)-related kinase 3
Target
NEK3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
52-60 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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