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MED17 antibody

Product Specifications

Background

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Synonyms

Mediator of RNA polymerase II transcription subunit 17|Activator-recruited cofactor 77 kDa component (ARC77)|Cofactor required for Sp1 transcriptional activation subunit 6 (CRSP complex subunit 6)|Mediator complex subunit 17|Thyroid hormone receptor-associated protein complex 80 kDa component (Trap80)|Transcriptional coactivator CRSP77|Vitamin D3 receptor-interacting protein complex 80 kDa component (DRIP80)|MED17|ARC77|CRSP6|DRIP77|DRIP80|TRAP80

Gene ID

9440

UniProt

Q9NVC6

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

mediator complex subunit 17

Target

MED17

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

80 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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