MED17 antibody
Product Specifications
Background
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Synonyms
Mediator of RNA polymerase II transcription subunit 17|Activator-recruited cofactor 77 kDa component (ARC77) |Cofactor required for Sp1 transcriptional activation subunit 6 (CRSP complex subunit 6) |Mediator complex subunit 17|Thyroid hormone receptor-associated protein complex 80 kDa component (Trap80) |Transcriptional coactivator CRSP77|Vitamin D3 receptor-interacting protein complex 80 kDa component (DRIP80) |MED17|ARC77|CRSP6|DRIP77|DRIP80|TRAP80
Gene ID
9440
UniProt
Q9NVC6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Mediator complex subunit 17
Target
MED17
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
80 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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