LRPPRC antibody
Product Specifications
Background
This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome.
Synonyms
Leucine-rich PPR motif-containing protein, mitochondrial|130 kDa leucine-rich protein (LRP 130)|GP130|LRPPRC|LRP130
Gene ID
10128
UniProt
P42704
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
leucine-rich PPR-motif containing
Target
LRPPRC
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:1000 - 1:2000; IHC: 1:100 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
140 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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