FNTA antibody
Product Specifications
Background
Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation.
Synonyms
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha|CAAX farnesyltransferase subunit alpha|FTase-alpha|Ras proteins prenyltransferase subunit alpha|Type I protein geranyl-geranyltransferase subunit alpha (GGTase-I-alpha) |FNTA
Gene ID
2339
UniProt
P49354
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Farnesyltransferase, CAAX box, alpha
Target
FNTA
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
44 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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