NRG4 (NM_138573) Human Recombinant Protein

Product Specifications

Background

The neuregulins, including NRG4, activate type-1 growth factor receptors (see EGFR; MIM 131550) to initiating cell-to-cell signaling through tyrosine phosphorylation (Harari et al., 1999 [PubMed 10348342]) .[supplied by OMIM, Mar 2008]

Overview

Purified recombinant protein of Human neuregulin 4 (NRG4), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

Synonyms

HRG4

Gene ID

145957

UniProt

Q8WWG1

Accession Number mRNA

NM_138573

Chromosomal Location

15q24.2

Expression System

E. coli

Tag

N-GST and C-His

Related Pathways

ErbB signaling pathway

Field of Research

ErbB signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

Function

Transmembrane

Molecular Weight

38.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.