NRG4 (NM_138573) Human Recombinant Protein
Product Specifications
Background
The neuregulins, including NRG4, activate type-1 growth factor receptors (see EGFR; MIM 131550) to initiating cell-to-cell signaling through tyrosine phosphorylation (Harari et al., 1999 [PubMed 10348342]) .[supplied by OMIM, Mar 2008]
Synonyms
HRG4
Gene ID
145957
UniProt
Q8WWG1
Accession Number mRNA
NM_138573
Chromosomal Location
15q24.2
Expression System
E. coli
Tag
N-GST and C-His
Related Pathways
ErbB signaling pathway
Field of Research
ErbB signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
Function
Transmembrane
Molecular Weight
38.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NRG4
Species
Human
Protein ID
NP_612640
Overview
Purified recombinant protein of Human neuregulin 4 (NRG4), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/145957
Uniprot URL
https://www.uniprot.org/uniprot/Q8WWG1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_138573
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_612640
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