ERCC6L antibody
Product Specifications
Background
DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.
Synonyms
DNA excision repair protein ERCC-6-like|ATP-dependent helicase ERCC6-like|PLK1-interacting checkpoint helicase|Tumor antigen BJ-HCC-15|ERCC6L|PICH
Gene ID
54821
UniProt
Q2NKX8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
excision repair cross-complementing rodent repair deficiency, complementation group 6-like
Target
ERCC6L
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Epigenetics, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
180 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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